Lynkuet (Elinzanetant): A Non-Hormonal Capsule for Menopause Symptoms

Managing hot flushes and night sweats during menopause just got a new option. The MHRA has recently approved Lynkuet (elinzanetant), a non-hormonal treatment for moderate to severe vasomotor symptoms associated with menopause. This is an exciting development for women who either cannot take, or prefer to avoid, hormone replacement therapy (HRT).

🔍 How does Lynkuet work?

Unlike HRT, which replaces declining hormones, Elinzanetant works by targeting specific brain pathways linked to temperature regulation. This makes it a valuable alternative for women seeking hormone-free menopause relief.

💊 Prescribing Guidelines

• Standard dose: 120mg once daily (two 60mg capsules), taken at bedtime. This may be reduced to one capsule for some women. 

Clinical trials show Lynkuet is generally well tolerated, offering a new option for women struggling with disruptive vasomotor symptoms. However, it is not recommended in women with severe liver or kidney impairment, or during pregnancy and breastfeeding.

Common side effects include headache, fatigue, and dizziness, though most are mild to moderate.

🌸 Why this matters for women’s health

Research shows only 5% of healthcare studies focus on women-specific conditions like menopause (McKinsey, 2022). The arrival of Lynkuet is a step forward in closing that gap, giving women more choice, dignity, and access to treatments that meet their unique needs.

❓ FAQs

1. What is Lynkuet (elinzanetant) used for?
   Lynkuet is prescribed to treat moderate to severe vasomotor symptoms (hot flushes and night sweats) during menopause.
2. How is Lynkuet different from HRT?
   Unlike HRT, which replaces hormones, Lynkuet is a non-hormonal option. It works on brain pathways regulating body temperature, making it suitable for women who can’t or don’t want HRT.
3. Are there side effects?
   Yes, some women may experience headache, fatigue, dizziness, or stomach upset, but these are usually mild. Always report persistent or severe side effects to your healthcare provider.
4. Can all women take Lynkuet?
   No. It’s not recommended for women who are pregnant, breastfeeding, or who have severe liver or kidney disease. Always check with a healthcare professional before starting treatment.
5. How do I access Lynkuet through TribElle?
   Watch this space! Lynkuet is still very new and access to patients is yet to be confirmed. In the meantime, you can consult our clinical team online, discuss whether Lynkuet is right for you.